GPR119 Agonists: A Novel Strategy for Type 2 Diabetes Treatment

نویسندگان

  • Xiaoyun Zhu
  • Wenglong Huang
  • Hai Qian
چکیده

Type 2 diabetes (T2DM), also known as non-insulin-dependent diabetes mellitus (NIDDM), manifests with an inability to adequately regulate blood-glucose levels. T2DM may be characterized by a defect in insulin secretion or by insulin resistance, namely those that suffer from T2DM have too little insulin or cannot use insulin effectively. Insulin resistance which refers to the inability of body tissues to respond properly to endogenous insulin develops because of multiple factors, including genetics, obesity, increasing age, and having high blood sugar over long periods of time[1].

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تاریخ انتشار 2013